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Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia

Restuadi Restuadi, Fleur C. Garton, Beben Benyamin, Tian Lin, Kelly L. Williams, Anna A. E. Vinkhuyzen, Wouter van Rheenen, Zhihong Zhu, Nigel G. Laing, Karen A. Mather, Perminder S. Sachdev, Shyuan T. Ngo, Frederik J. Steyn, Leanne Wallace, Anjali K. Henders, Peter M. Visscher, Merrilee Needham, Susan Mathers, Garth A. Nicholson, Dominic B. Rowe, Robert D. Henderson, Pamela McCombe, Roger Pamphlett, Ian P. Blair, Naomi R. Wray, Allan F. McRae

2021European Journal of Human Genetics26 citationsDOIOpen Access PDF

Topics & Concepts

Amyotrophic lateral sclerosisPolygenic risk scoreSchizophrenia (object-oriented programming)CognitionPsychologyLod scoreMedicineNeuroscienceClinical psychologyGeneticsPhysical medicine and rehabilitationBiologyPsychiatryInternal medicineDiseaseSingle-nucleotide polymorphismGeneGenotypeGene mappingChromosomeAmyotrophic Lateral Sclerosis ResearchNeurological diseases and metabolismCancer-related gene regulation
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