“Trojan horse” nanoparticle-delivered cancer cell membrane vaccines to enhance cancer immunotherapy by overcoming immune-escape
Jingjing Wang, Bing Sun, Luyao Sun, Xueming Niu, Li Li, Zhi Ping Xu
Abstract
A biomimetic CpG-layered double hydroxide nanoparticle-engineered cancer cell membrane nano-vaccine with mannose conjugation to boost anti-cancer immunity with a long-term anti-tumor immune response was proposed.
Topics & Concepts
Immune systemCancer immunotherapyCancer vaccineAntigenImmunotherapyCancer cellCancerAdjuvantCancer researchImmunologyBiologyGeneticsImmunotherapy and Immune ResponsesNanoplatforms for cancer theranosticsRNA Interference and Gene Delivery