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Case Report and Literature Review: Catastrophic Embolism Following Cosmetic Injection of Autologous Fat in the Face

Chunyu Liu, Zhaolun Cai, Lingli Zhang, Muke Zhou, Li He

2021Frontiers in Medicine15 citationsDOIOpen Access PDF

Abstract

Injection of autologous fat on the face is a commonly performed procedure in plastic surgery. However, it can lead to rare but devastating complications due to fat embolism. In this study, we presented two cases of cerebral infarction and/or sudden vision loss after cosmetic injections of autologous fat on the face. Two women underwent injections into the temporal and frontal areas, respectively. In case 1, the patient underwent decompressive craniectomy as her condition deteriorated continuously and died. In case 2, the patient's vision had not improved at the 3-month follow-up visit. Imaging examinations showed occlusion of the right external carotid artery in case 1, and multiple retinal arterioles were segmentally occluded in case 2. We also screened relevant studies via a systematic search of PubMed (last updated on May 9, 2020) and performed a narrative review due to the significant heterogeneity between the studies. To prevent this catastrophic event, the autologous fat injection should be performed carefully. If embolization does occur, early diagnosis and timely treatment may help improve functional outcomes.

Topics & Concepts

MedicineFat embolismSurgeryEmbolizationEmbolismDecompressive craniectomyOcclusionNarrative reviewRetinal Artery OcclusionRetinalTraumatic brain injuryOphthalmologyIntensive care medicinePsychiatryFacial Rejuvenation and Surgery TechniquesFacial Nerve Paralysis Treatment and ResearchDermatologic Treatments and Research
Case Report and Literature Review: Catastrophic Embolism Following Cosmetic Injection of Autologous Fat in the Face | Litcius