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Implications of frequent hitter E3 ligases in targeted protein degradation screens

Xiaoyu Zhang, Gabriel M. Simon, Benjamin F. Cravatt

2025Nature Chemical Biology31 citationsDOIOpen Access PDF

Topics & Concepts

UbiquitinDegradation (telecommunications)Protein degradationComputational biologyBiologyComputer scienceChemistryCell biologyGeneticsGeneTelecommunicationsProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors Research
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