Polyoxometalate–polypeptide nanoassemblies as peroxidase surrogates with antibiofilm properties
Héctor Soria‐Carrera, Elena Atrián‐Blasco, Jesús M. de la Fuente, Scott G. Mitchell, Rafael Martín‐Rapún
Abstract
; whereas, ionic POM-peptide hybrids significantly increase biofilm production and endogenous production of reactive oxygen species. In summary, we present the self-assembly of POMlymer hybrids into nanoparticles and a combination of peroxidase activity and microbiology assays that show that the POM-peptide covalent bond is essential for the stability of the self-assembled nanoparticles and therefore for their catalytic and biological activity.
Topics & Concepts
ChemistryPolyoxometalateCovalent bondSupramolecular chemistryCatalysisPeptideNanoparticleCombinatorial chemistryIonic bondingPeroxidaseOrganic chemistryNanotechnologyEnzymeMaterials scienceMoleculeBiochemistryIonPolyoxometalates: Synthesis and ApplicationsSulfur-Based Synthesis TechniquesAdvanced Nanomaterials in Catalysis