Breaking NGF–TrkA immunosuppression in melanoma sensitizes immunotherapy for durable memory T cell protection
Tao Yin, Guoping Wang, Liuyang Wang, Poorva Mudgal, Ergang Wang, Christopher C. Pan, Peter B. Alexander, Haiyang Wu, Chengjie Cao, Yaosi Liang, Lianmei Tan, De Huang, Mengyang Chong, Rui Chen, Bryan Jian Wei Lim, Kun Xiang, Wei Xue, Lixin Wan, Hailan Hu, Yuin‐Han Loh, Xiao‐Fan Wang, Qi-Jing Li
Topics & Concepts
ImmunosuppressionImmunotherapyMelanomaImmunologyMedicineTropomyosin receptor kinase ANeuroimmunologyCancer researchNerve growth factorImmune systemReceptorInternal medicineCAR-T cell therapy researchImmunotherapy and Immune ResponsesMelanoma and MAPK Pathways