Relationship between Diagnostic Method and Pathogen Detection, Healthcare Resource Use, and Cost in U.S. Adult Outpatients Treated for Acute Infectious Gastroenteritis
Rena C. Moon, Tammy C Bleak, Ning Rosenthal, Brianne Couturier, Rachael Hemmert, Tristan T. Timbrook, Harold Brown, Ferric C. Fang
Abstract
A retrospective observational study was performed to assess the relationship between diagnostic method (traditional work-up [TW], multiplex PCR panel with < 12 target pathogens [PCR < 12], or multiplex PCR panel with ≥ 12 target pathogens [PCR12]), and diagnostic yield, health care resource use (HRU), and cost in adult outpatients visiting U.S. hospitals for acute infectious gastroenteritis (AGE). Using data from PINC AI Healthcare Database during January 1, 2016–June 30, 2021, we analyzed adult patients with an AGE diagnosis and stool testing performed during an outpatient visit.
Topics & Concepts
MedicineMultiplex polymerase chain reactionRetrospective cohort studyInternal medicinePathogenObservational studyDiagnostic testAntibioticsPediatricsPolymerase chain reactionImmunologyBiologyMicrobiologyGeneBiochemistryViral gastroenteritis research and epidemiologyClostridium difficile and Clostridium perfringens researchSalmonella and Campylobacter epidemiology