Litcius/Paper detail

Design, synthesis, and biological evaluation of indole-based hydroxamic acid derivatives as histone deacetylase inhibitors

Beier Jiang, Jiaxin Hu, Hao Liu, Zhitao Liu, Yuquan Wen, Mingyao Liu, Hankun Zhang, Xiufeng Pang, Li-Fang Yu

2021European Journal of Medicinal Chemistry29 citationsDOIOpen Access PDF

Topics & Concepts

AcetylationHydroxamic acidChemistryHDAC6Histone deacetylaseHDAC1Histone H3VorinostatIC50HistoneBiochemistryHDAC8Histone deacetylase 2Cell growthApoptosisHDAC10In vitroStereochemistryGeneHistone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsPeptidase Inhibition and Analysis
Design, synthesis, and biological evaluation of indole-based hydroxamic acid derivatives as histone deacetylase inhibitors | Litcius