A new ketogenic formulation improves functional outcome and reduces tissue loss following traumatic brain injury in adult mice
Orli Thau‐Zuchman, Linda Svendsen, Simon C. Dyall, Ursula Paredes-Esquivel, Molly Rhodes, John V. Priestley, René G. Feichtinger, Barbara Kofler, Susanne Lotstra, J. Martin Verkuyl, Robert Hageman, Laus M. Broersen, Nick van Wijk, José Silva, Jordi L. Tremoleda, Adina T. Michael‐Titus
Abstract
The behavioural improvement and tissue protection provide proof of principle that this new formulation has therapeutic potential in adult TBI.
Topics & Concepts
Ketogenic dietTraumatic brain injuryNeuroprotectionMedicineInflammationLesionInternal medicineDocosahexaenoic acidEndocrinologyPharmacologyChemistryBiochemistryPathologyEpilepsyFatty acidPsychiatryPolyunsaturated fatty acidDiet and metabolism studiesMetabolism and Genetic DisordersMitochondrial Function and Pathology