Design and synthesis of new 4-methylthiazole derivatives: In vitro and in silico studies of antimicrobial activity
Asaf Evrim Evren, Sam Dawbaa, Demokrat Nuha, Şule Aybüke Yavuz, Ülküye Dudu Gül, Leyla Yurttaş
Topics & Concepts
AntimicrobialChemistryAllosteric regulationThiazoleCombinatorial chemistryDNA gyraseIn silicoStereochemistryHeteronuclear single quantum coherence spectroscopyDocking (animal)Computational biologyTwo-dimensional nuclear magnetic resonance spectroscopyBiochemistryEscherichia coliOrganic chemistryEnzymeBiologyMedicineNursingGeneSynthesis and biological activityClick Chemistry and ApplicationsComputational Drug Discovery Methods