Oxidation-derived anticancer potential of sumanene–ferrocene conjugates
Artur Kasprzak, Agnieszka Żuchowska, Paweł Romanczuk, Agata Kowalczyk, Ireneusz P. Grudziński, Anna Małkowska, Anna M. Nowicka, Hidehiro Sakurai
Abstract
computational analysis also showed no chromosomal aberrations and no mutation with AMES tests for the compound 7 tested with and without microsomal rat liver fractions, which supports its further use as a potent drug candidate in detailed anticancer studies.
Topics & Concepts
ChemistryFerroceneConjugateIn vitroCancer cellCombinatorial chemistryConjugated systemStereochemistryBiochemistryCancerOrganic chemistryElectrochemistryMathematical analysisPolymerElectrodeInternal medicinePhysical chemistryMedicineMathematicsFerrocene Chemistry and ApplicationsSynthetic Organic Chemistry MethodsMetal complexes synthesis and properties