Coordination-driven FBXW7 DNAzyme-Fe nanoassembly enables a binary switch of breast cancer cell cycle checkpoint responses for enhanced ferroptosis-radiotherapy
Jiawu Yu, Yuchen Zhang, Liqi Li, Yang Xiang, Xuemei Yao, Youbo Zhao, Kaiyong Cai, Menghuan Li, Zhongjun Li, Zhong Luo, Zhong Luo
Topics & Concepts
Cancer researchRadiation therapyBreast cancerCancer cellCancerRadioresistanceMaterials scienceDNA damageCell cycle checkpointCell cycleCell biologyChemistryBiologyMedicineInternal medicineDNABiochemistryEpigenetics and DNA MethylationFerroptosis and cancer prognosisRNA modifications and cancer