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Microchip Electrophoresis

Sammer-ul Hassan

2020Encyclopedia15 citationsDOIOpen Access PDF

Abstract

Microchip electrophoresis (MCE) is a miniaturized form of capillary electrophoresis. Electrophoresis is a common technique to separate macromolecules such as nucleic acids (DNA, RNA) and proteins. This technique has become a routine method for DNA size fragmenting and separating protein mixtures in most laboratories around the world. The application of higher voltages in MCE achieves faster and efficient electrophoretic separations.

Topics & Concepts

ElectrophoresisCapillary electrophoresisNucleic acidFree-flow electrophoresisDNAChemistryGel electrophoresis of nucleic acidsGel electrophoresis of proteinsChromatographyGel electrophoresisPolyacrylamide gel electrophoresisBiochemistryEnzymeMicrofluidic and Capillary Electrophoresis ApplicationsMicrofluidic and Bio-sensing TechnologiesElectrowetting and Microfluidic Technologies