Safety, pharmacokinetics, and pharmacodynamics of pegozafermin in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 1b/2a multiple-ascending-dose study
Rohit Loomba, Eric Lawitz, Juan P. Frías, Grisell Ortiz‐Lasanta, L. E. B. Johansson, Bridgette Boggess Franey, Linda Morrow, Moti Rosenstock, Cynthia L. Hartsfield, Chaoyin Chen, Leo Tseng, R. Will Charlton, Hank Mansbach, Maya Margalit
Topics & Concepts
MedicineSteatohepatitisPlaceboTolerabilityPharmacokineticsInternal medicineFatty liverClinical endpointPharmacodynamicsGastroenterologyRandomized controlled trialAdverse effectDiseasePathologyAlternative medicineLiver Disease Diagnosis and TreatmentFibroblast Growth Factor ResearchBariatric Surgery and Outcomes