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Current therapy option for necrotizing enterocolitis: Practicalities and challenge

Huihuan Wu, Kehang Guo, Zewei Zhuo, Ruijie Zeng, Yujun Luo, Qi Yang, Jingwei Li, Rui Jiang, Zena Huang, Weihong Sha, Hao Chen

2022Frontiers in Pediatrics19 citationsDOIOpen Access PDF

Abstract

Necrotizing enterocolitis (NEC) is one of the most prevalent neonatal gastrointestinal disorders. Despite ongoing breakthroughs in its treatment and prevention, the incidence and mortality associated with NEC remain high. New therapeutic approaches, such as breast milk composition administration, stem cell therapy, immunotherapy, and fecal microbiota transplantation (FMT) have recently evolved the prevention and the treatment of NEC. This study investigated the most recent advances in NEC therapeutic approaches and discussed their applicability to bring new insight to NEC treatment.

Topics & Concepts

MedicineNecrotizing enterocolitisIntensive care medicineEnterocolitisRescue therapyIncidence (geometry)TransplantationPediatricsInternal medicineOpticsPhysicsInfant Nutrition and HealthNeonatal Respiratory Health ResearchBreastfeeding Practices and Influences