Synthesis of noradamantane building blocks
Matthew J. Todd, Ivana Cı́sařová, Zdeněk Tošner, Radim Hrdina
Abstract
The carbon scaffold of noradamantane, a ring contracted adamantane derivative, is notoriously difficult to selectively oxidise and functionalise, which limits the hydrocarbon's use as a building block for preparing noradamantyl decorated targets.
Topics & Concepts
ChemistryBlock (permutation group theory)AdamantaneRing (chemistry)ScaffoldNanotechnologyCombinatorial chemistryCarbon fibersSolid-stateSolid-phase synthesisComputational Drug Discovery Methods