Thermodynamic dissection of the interface between HIV-1 gp41 heptad repeats reveals cooperative interactions and allosteric effects
Samuel Jurado, Mario Cano‐Muñoz, Daniel Polo-Megías, Francisco Conejero‐Lara, Bertrand Morel
Topics & Concepts
Heptad repeatGp41Allosteric regulationChemistryCoiled coilBiophysicsFusionLipid bilayer fusionTrimerBinding siteComputational biologyBiologyBiochemistryPeptide sequenceGeneticsDimerGeneMembranePhilosophyEpitopeEnzymeOrganic chemistryLinguisticsAntigenHIV Research and TreatmentMonoclonal and Polyclonal Antibodies ResearchRNA and protein synthesis mechanisms