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Pulmonary Embolism and Increased Levels of <scp>d</scp>-Dimer in Patients with Coronavirus Disease

Daniel O. Griffin, Alexandra Jensen, Mushmoom Khan, Jessica Chin, Kelly Chin, Jennifer Saad, Ryan Parnell, Christopher Awwad, Darshan P. Patel

2020Emerging infectious diseases94 citationsDOIOpen Access PDF

Abstract

We report 3 patients with coronavirus disease who had a decline in respiratory status during their hospital course that responded well to intravenous steroids and interleukin-6 receptor antagonist therapy. These patients later showed development of persistent hypoxia with increased levels of d-dimer levels and were given a diagnosis of pulmonary embolisms.

Topics & Concepts

D-dimerPulmonary embolismCoronavirusCoronavirus disease 2019 (COVID-19)MedicineHypoxia (environmental)DiseaseInterleukin 1 receptor antagonistInternal medicineRespiratory systemSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)TocilizumabImmunologyGastroenterologyReceptorAntagonistReceptor antagonistInfectious disease (medical specialty)ChemistryOxygenOrganic chemistryCOVID-19 Clinical Research StudiesThermal Regulation in MedicineLong-Term Effects of COVID-19