Fast unmasking toxicity of safe personal care products
Gertrud E. Morlock, Luisa Zoller
Abstract
) of around 60 µg of such products which can easily be exceeded by a factor of 100,000 for only 6 g product applied or for an aggregated use of various products increasing genotoxic exposure, as observed in consumer profiles. Simulated metabolization via S9 liver enzymes did not lead to detoxification. The new safety screening not only unmasked quickly the toxicity of personal care products but also provided an understanding of how to produce hazard-free products. It empowers industries to produce future products in compliance with their standards and claims in terms of consumer health, ethics, environmental compatibility, and sustainability, and authorities to control the safety of products on the market and tackle the current underregulation.