Nanoassemblies Based on a Cationic Perylene Diimide Derivative and Sodium Dodecyl Sulfate: A Simple Fluorescent Platform for Efficient Analysis of Aflatoxin B<sub>1</sub>
Zhefei Zhao, Tianyue Liu, Jinghui Gao, Qiaojuan Zhang, Mengyu Liao, Cheng He, Jingsheng Tian, Zhiyi Yao
Abstract
Aflatoxin B 1 (AFB 1 ) is a kind of potently carcinogenic fungal metabolite in food threatening human health, and it is crucial and challenging to develop advanced nonimmune approaches for AFB 1 determination. Addressing this challenge, we successfully constructed a nanoassembly (PdE-PDI/SDS) by noncovalently coupling a cationic perylene diimide derivative (PdE-PDI) and sodium dodecyl sulfate (SDS), exhibiting high-density charges and a specific surface area for rapid sensing of AFB 1 . The large electronic conjugate structure and rigid plane of PdE-PDI enable it to form more stable σ–π, π–π coordination, and hydrogen bonds with AFB 1 . Additionally, the introduction of SDS significantly amplifies noncovalent interactions and enhances the quenching efficiency of PdE-PDI toward AFB 1 . The proposed PdE-PDI/SDS exhibited excellent specificity to AFB 1 and showed dosage-sensitive detection with detection limit as low as 0.74 ng mL –1 . Finally, the PdE-PDI/SDS was successfully applied in cereal samples with good recoveries from 94.61 to 109.92%. To our knowledge, this is the first time a fluorescent strategy from the point of self-assembly for AFB 1 determination is reported, which holds great promise for wide applications of perylene diimide derivative in food safety.