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Human Skin Microbiome: Impact of Intrinsic and Extrinsic Factors on Skin Microbiota

Krzysztof Skowron, Justyna Bauza-Kaszewska, Zuzanna Kraszewska, Natalia Wiktorczyk-Kapischke, Katarzyna Grudlewska‐Buda, Joanna Kwiecińska-Piróg, Ewa Wałecka-Zacharska, Laura Radtke, Eugenia Gospodarek-Komkowska

2021Microorganisms338 citationsDOIOpen Access PDF

Abstract

The skin is the largest organ of the human body and it protects the body from the external environment. It has become the topic of interest of researchers from various scientific fields. Microorganisms ensure the proper functioning of the skin. Of great importance, are the mutual relations between such microorganisms and their responses to environmental impacts, as dysbiosis may contribute to serious skin diseases. Molecular methods, used for microorganism identification, allow us to gain a better understanding of the skin microbiome. The presented article contains the latest reports on the skin microbiota in health and disease. The review discusses the relationship between a properly functioning microbiome and the body's immune system, as well as the impact of internal and external factors on the human skin microbiome.

Topics & Concepts

MicrobiomeDysbiosisHuman skinIdentification (biology)Human healthBiologyImmune systemHuman microbiomeHuman bodyHuman Microbiome ProjectDiseaseImmunologyEcologyMedicineBioinformaticsGeneticsEnvironmental healthPathologyAnatomyDermatology and Skin DiseasesSkin Protection and AgingAcne and Rosacea Treatments and Effects
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