Design and synthesis of eugenol/isoeugenol glycoconjugates and other analogues as antifungal agents against <i>Aspergillus fumigatus</i>
Lakshmi Goswami, Lovely Gupta, Sayantan Paul, Maansi Vermani, Pooja Vijayaraghavan, Asish K. Bhattacharya
Abstract
values of 5.42 and 9.39 μM, respectively. The study suggested that these two analogues inhibit cell wall-associated melanin hydrophobicity along with the number of conidia. The synthesized compounds were found to be non-cytotoxic to an untransformed cell line.
Topics & Concepts
Aspergillus fumigatusIsoeugenolEugenolAntifungalGlycoconjugateMicrobiologyChemistryAntiparasiticBiologyBiochemistryMedicineOrganic chemistryPathologyAntifungal resistance and susceptibilitySynthesis and Biological EvaluationFungal Plant Pathogen Control