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Regioselective synthesis of N-containing polycyclic compounds <i>via</i> radical annulation cyclization of 1,7-dienes with aldehydes

Jia-Li Sui, Long‐Jin Zhong, Biquan Xiong, Kewen Tang, Yu Liu

2024Chemical Communications10 citationsDOI

Abstract

]quinolinone derivatives by sequential formation of three new carbon-carbon bonds. Additionally, this radical cascade cyclization can selectively convert aldehydes into aroyl/primary aliphatic acyl radicals and secondary or tertiary alkyl radicals.

Topics & Concepts

AnnulationRegioselectivityChemistryAlkylationAcylationOrganic chemistryRadical cyclizationCascadeCombinatorial chemistryCatalysisChromatographyRadical Photochemical ReactionsOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization Methods
Regioselective synthesis of N-containing polycyclic compounds <i>via</i> radical annulation cyclization of 1,7-dienes with aldehydes | Litcius