Development of a novel apixaban-loaded solid self-emulsifying drug delivery system for oral administration: physicochemical characterization and pharmacokinetics in rats
Hye In Lee, Mi Ran Woo, Fakhar ud Din, Jung Suk Kim, Seunghyun Cheon, Seonghyeon Park, Sanghyun Woo, Sung Giu Jin, Han‐Gon Choi
Topics & Concepts
BioavailabilitySolubilityChromatographyDistilled waterDissolutionDissolution testingChemistryDifferential scanning calorimetryMaterials scienceChemical engineeringPharmacologyOrganic chemistryBiopharmaceutics Classification SystemMedicineThermodynamicsEngineeringPhysicsDrug Solubulity and Delivery SystemsSurfactants and Colloidal SystemsAdvanced Drug Delivery Systems