Active and Effective Measures for the Care of Patients With Cancer During the COVID-19 Spread in China

Abstract

Active and Effective Measures for the Care of Patients With Cancer During the COVID-19 Spread in ChinaRecently, an outbreak of the highly infectious novel coronavirus disease 2019 (COVID-19) has swept Wuhan, China, with 80 303 confirmed diagnosed cases in China as of March 3, 2020. 1 Considering its high risk of person-toperson transmission, hospitals, especially in China, are the typical congregating places that will bear the brunt of this infectious disease.To reduce or avoid cross infection of COVID-19, many hospitals have started taking actions to limit the number of outpatient visits and inpatient admissions.For example, only emergency surgeries can be guaranteed, while most others are postponed.Maintenance chemotherapy and/or immunotherapy treatments for patients with advanced cancer are often suspended.However, forced delays or interruptions of routine treatment might increase the risk of disease deterioration, especially for patients with cancer.In China, approximately 4.3 million cases of cancer are diagnosed each year. 2 During the epidemic of COVID-19, the treatment of patients with cancer, which is often considered as nonemergent, is inevitably affected across China, especially in Wuhan.As a result of powerful prevention and control measures, the spread of COVID-19 has been gradually controlled.However, cases have been diagnosed in a number ofcountriesoutsideofChina,especiallyinSouthKoreaand Iran, leading to a global outbreak.As of March 3, 2020, newly diagnosed cases and deaths owing to COVID-19 had occurred in nearly 70 countries or regions, including South Korea,Iran,Italy,Japan,Germany,Singapore,Spain,andthe US,withatotalof11 953confirmedcases. 3 Theinsidiousonset (which can manifest without any obvious clinical symptoms, such as fever, in the early phase) and long incubation period (up to 24 days 4 ) indicate the strong transmissibility of COVID-19.The World Health Organization has declared COVID-19tobea"publichealthemergencyofinternational concern." 5 Therefore,itmayhaveaworldwideinfluenceon the diagnosis and treatment of patients with cancer.Patientswithcancerareusuallycharacterizedbyolder ages, multiple complicated diseases, and lower immunity, meaning a higher probability of severe illness and increased mortality compared with the healthy population once infected with COVID-19. 6To alleviate the difficulties of patients with cancer in seeking medical aid and simultaneously avoid COVID-19-related nosocomial cross infection between patients and medical staff, several mandatory measures are being carried out in the National Cancer Center/Cancer Hospital, Chinese Academy of Sciences during this period.First,multipleon-sitetemperaturetestsareperformed at the entrances of the hospital, the outpatient clinic, and

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