Neutralization of SARS-CoV-2 Omicron BA.2.75 after mRNA-1273 Vaccination
Xiaoying Shen, Spyros Chalkias, Jing Feng, Xing Chen, Honghong Zhou, Jean‐Claude Marshall, Bethany Girard, Joanne E. Tomassini, Anne Aunins, Rituparna Das, David C. Montefiori
Abstract
ened neutralization escape.Overall, vaccine efficacy against BA.2.75 is expected to be similar to that against BA.1 and BA.2.Whether and by how much another vaccine booster, particularly one containing an omicron spike, would elicit a more potent response against BA.2.75 and future SARS-CoV-2 variants remains of high interest for vaccine development.
Topics & Concepts
NeutralizationVirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VaccinationCoronavirus disease 2019 (COVID-19)Booster (rocketry)2019-20 coronavirus outbreakMedicineInfectious disease (medical specialty)PhysicsOutbreakVirusInternal medicineDiseaseAstronomySARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections StudiesViral gastroenteritis research and epidemiology