A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein
Xiuxiu Yang, Haiyu Li, Xiaofang Zhao, Wei Liao, Claire Xi Zhang, Zhongqiang Yang
Abstract
A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnosis, but also provides a general platform for detection based on DNA aptamer.
Topics & Concepts
BiosensorAlpha-synucleinAptamerDNAAlpha (finance)ChemistryNanotechnologyParkinson's diseaseMaterials scienceDiseaseMolecular biologyMedicineBiologyBiochemistryPathologySurgeryPatient satisfactionConstruct validityParkinson's Disease Mechanisms and TreatmentsConducting polymers and applicationsGenetic Neurodegenerative Diseases