HIF1α promotes tumor chemoresistance via recruiting GDF15-producing TAMs in colorectal cancer
Hongtu Zheng, Shan Yu, Congcong Zhu, Tianan Guo, Fangqi Liu, Ye Xu
Topics & Concepts
Colorectal cancerCancer researchBiologyTumor-associated macrophageChemotherapyImmune systemInfiltration (HVAC)Tumor microenvironmentTranscription factorTumor progressionCancerImmunologyGeneTumor cellsBiochemistryThermodynamicsPhysicsGeneticsGDF15 and Related BiomarkersMacrophage Migration Inhibitory FactorHistone Deacetylase Inhibitors Research