Litcius/Paper detail

Dissecting how ALS-associated D290V mutation enhances pathogenic aggregation of hnRNPA2286–291 peptides: Dynamics and conformational ensembles

Yuan Tan, Yujie Chen, Xianshi Liu, Yiming Tang, Zenghui Lao, Guanghong Wei

2023International Journal of Biological Macromolecules13 citationsDOI

Topics & Concepts

Molecular dynamicsMutationStackingChemistryBiophysicsPeptideHydrogen bondConformational ensemblesBiochemistryBiologyComputational chemistryGeneMoleculeOrganic chemistryRNA Research and SplicingAmyotrophic Lateral Sclerosis ResearchRNA and protein synthesis mechanisms