Litcius/Paper detail

Progress in the Research and Development of Anti-COVID-19 Drugs

Lianzhou Huang, Yuanqiu Chen, Ji Xiao, Weisheng Luo, Li Feng, Yuan Wang, Yuan Wang, Yiliang Wang, Yiliang Wang, Yifei Wang, Yifei Wang

2020Frontiers in Public Health26 citationsDOIOpen Access PDF

Abstract

The outbreaks of COVID-19 due to SARS-CoV-2 has caused serious physical and psychological damage to global human health. COVID-19 spread rapidly around the world in a short time. Confronted with such a highly infectious respiratory disease, the research and development of anti-COVID-19 drugs became an urgent work due to the lack of specific drugs for the treatment of COVID-19. Nevertheless, several existing drugs are available to relieve the clinical symptoms of COVID-19. We reviewed information on selected anti-SARS-CoV-2 candidate therapeutic agents published until June 2, 2020. We also discussed the strategies of the development of anti-COVID-19 drugs in the future. Our review provides a novel insight into the future development of a safer, efficient, and toxic-less anti-COVID-19 drug.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Drug developmentSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakMedicineSAFERPandemicIntensive care medicineOutbreakInfectious disease (medical specialty)DrugDiseaseVirologyPharmacologyComputer sciencePathologyComputer securityCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchPharmacological Receptor Mechanisms and Effects