ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer’s disease
Seong Su Kang, Eun Hee Ahn, Xia Liu, Matthew Bryson, Gary W. Miller, David Weinshenker, Keqiang Ye
Topics & Concepts
Locus coeruleusNeurotoxicityNeurodegenerationMonoamine neurotransmitterChemistryNeuroscienceSynaptic vesicleHippocampal formationInternal medicineBiologyEndocrinologyBiochemistryMedicineVesicleCentral nervous systemSerotoninToxicityDiseaseMembraneReceptorAlzheimer's disease research and treatmentsNeuroscience and Neuropharmacology ResearchCellular transport and secretion