A Selective and General Cobalt‐Catalyzed Hydroaminomethylation of Olefins to Amines
Ji Yang, Fábio G. Delolo, Anke Spannenberg, Ralf Jackstell, Matthias Beller
Abstract
A new cobalt catalyst is presented for the domino hydroformylation-reductive amination reaction of olefins. The optimal Co-tert-BuPy-Xantphos catalyst shows good to excellent linear-to-branched (n/iso) regioselectivity for the reactions of aliphatic alkenes with aromatic amines under mild conditions. This system is far more selective than traditional cobalt(I) catalysts and even better than most known rhodium catalysts.
Topics & Concepts
HydroformylationXantphosCobaltCatalysisChemistryRegioselectivityRhodiumAminationOrganic chemistryCombinatorial chemistryPalladiumAsymmetric Hydrogenation and CatalysisCarbon dioxide utilization in catalysisOrganometallic Complex Synthesis and Catalysis