Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage
Tatyana Danyukova, Assil‐Ramin Alimy, Renata Voltolini Velho, Timur Yorgan, Giorgia Di Lorenzo, Simon von Kroge, Henning Tidow, J. Simon Wiegert, Irm Hermans‐Borgmeyer, Thorsten Schinke, Tim Rolvien, Sandra Pohl
Topics & Concepts
Osteogenesis imperfectaHaploinsufficiencyOsteocyteCartilageChondrocyteEndochondral ossificationPathologyOsteoarthritisPhenotypeBiologyMedicineAnatomyOsteoblastGeneticsGeneAlternative medicineIn vitroConnective tissue disorders researchUbiquitin and proteasome pathwaysCancer-related gene regulation