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Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases

Juan Mangas‐Sánchez, Mahima Sharma, Sebastian C. Cosgrove, Jeremy I. Ramsden, James R. Marshall, Thomas W. Thorpe, Ryan B. Palmer, Gideon Grogan, Nicholas J. Turner

2020Chemical Science76 citationsDOIOpen Access PDF

Abstract

RedAm highlight their potential for wider synthetic application as well as expanding the biocatalytic toolbox available for chiral amine synthesis.

Topics & Concepts

Primary (astronomy)CatalysisCombinatorial chemistryChemistryReductive aminationOrganic chemistryPhysicsAstronomyEnzyme Catalysis and ImmobilizationCyclopropane Reaction MechanismsClick Chemistry and Applications
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