Andrographolide upregulates protein quality control mechanisms in cell and mouse through upregulation of mTORC1 function

Naibedya Dutta, Suvranil Ghosh, Vinod Kumar Nelson, HOSSAINOOR RAHAMAN SARENG, Chirantan Majumder, Subhash C. Mandal, Mahadeb Pal

2021Biochimica et Biophysica Acta (BBA) - General Subjects26 citationsDOI

Topics & Concepts

AndrographolideHSF1Sequestosome 1Downregulation and upregulationmTORC1Cell biologyChemistryHeat shockMAPK/ERK pathwayHeat shock proteinBiologyPI3K/AKT/mTOR pathwaySignal transductionAutophagyHsp70BiochemistryApoptosisGeneAndrographolide Research and ApplicationsEndoplasmic Reticulum Stress and DiseaseHeat shock proteins research