Designing a multi-epitope vaccine against SARS-CoV-2: an immunoinformatics approach
Abdus Samad, Foysal Ahammad, Zulkar Nain, Rahat Alam, Raihan Rahman Imon, Mahadi Hasan, Md. Shahedur Rahman
Abstract
K12 resulted in optimal GC content and higher CAI value followed by incorporating it into the cloning vector pET28+(a). Overall, these results suggest that the designed peptide vaccine can serve as an excellent prophylactic candidate against SARS-CoV-2.Communicated by Ramaswamy H. Sarma.
Topics & Concepts
EpitopeVirologyImmune systemVaccinationImmunologyAntigenVaccine efficacyOutbreakCoronavirusBiologyMedicineDiseaseCoronavirus disease 2019 (COVID-19)Infectious disease (medical specialty)Pathologyvaccines and immunoinformatics approachesSARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Research