The enteroprotective effect of nifuroxazide against methotrexate-induced intestinal injury involves co-activation of PPAR-γ, SIRT1, Nrf2, and suppression of NF-κB and JAK1/STAT3 signals
Esraa K. Abd‐alhameed, Amany A. Azouz, Amira M. Abo‐Youssef, Fares E.M. Ali
Topics & Concepts
PharmacologyMethotrexateToxicityMedicineImmunohistochemistryTolerabilityInflammationProinflammatory cytokineInternal medicineAdverse effectChemotherapy-induced organ toxicity mitigationAcute Lymphoblastic Leukemia researchGenomics, phytochemicals, and oxidative stress