Clinical and biological data on the use of hydroxychloroquine against SARS‐CoV‐2 could support the role of the NLRP3 inflammasome in the pathogenesis of respiratory disease
Alessandro Lucchesi, Paolo Silimbani, Gerardo Musuraca, Claudio Cerchione, Giovanni Martinelli, Paola Di Carlo, Mariasanta Napolitano
Abstract
The use of hydroxychloroquine (HCL) has been very common in countries with a rapid spread of coronavirus disease 2019 (COVID-19), although controversial and the subject of heated scientific discussions with implications for the whole society. This article is protected by copyright. All rights reserved.
Topics & Concepts
HydroxychloroquineVirologyPathogenesisSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)InflammasomeCoronavirus disease 2019 (COVID-19)Disease2019-20 coronavirus outbreakMedicineHighly pathogenicImmunologyBiologyVirusInfectious disease (medical specialty)InflammationPathologyOutbreakInfluenza A virus subtype H5N1Inflammasome and immune disordersCOVID-19 Clinical Research StudiesHeme Oxygenase-1 and Carbon Monoxide