LncRNA NEAT1 affects endometrial receptivity by regulating HOXA10 promoter activity
Jiaxuan Geng, Chenchen Cui, Yisha Yin, Yan Zhao, Cuilian Zhang
Abstract
. Our study suggested that lncRNA NEAT1 could up-regulate HOXA10 promoter activity and its expression by combining with CTCF, thus improving EECs proliferation and ER establishment, and ultimately facilitating embryo implantation.
Topics & Concepts
CTCFBiologyEmbryoCell biologyEmbryo transferCancer researchGene expressionGeneticsGeneEnhancerReproductive System and PregnancyCancer-related molecular mechanisms researchHistorical Gender and Feminism Studies