Dermatologic toxicities associated with radiation therapy in women with breast cancer
Julie Y. Ramseier, Michelle Ferreira, Jonathan S. Leventhal
Abstract
Breast-conserving surgery with adjuvant radiation therapy has become the standard of care for women with early stage breast cancer, and as a result, a large number of patients are affected by the cutaneous sequelae of radiation therapy. These dermatologic toxicities may present during treatment or years later and can significantly impact patients' quality of life. In this review, we discuss the clinical presentation, prevention, and management of radiation-induced cutaneous toxicities in women with breast cancer, including radiation dermatitis, radiation recall, radiation-induced morphea, radiation-induced fibrosis, and cutaneous malignancies in irradiated skin.
Topics & Concepts
MedicineBreast cancerRadiation therapyDermatologyMorpheaAdjuvant radiotherapyCancerOncologyInternal medicineLichen sclerosusChemotherapy-related skin toxicityCancer and Skin LesionsCancer Diagnosis and Treatment