Chronic exposure to (2 R,6 R)-hydroxynorketamine induces developmental neurotoxicity in hESC-derived cerebral organoids
Zhulin Du, Zhenle Zang, Jing Luo, Tianyao Liu, Ling Yang, Yun Cai, Liuyongwei Wang, Dandan Zhang, Jinghui Zhao, Junwei Gao, Keyi Lv, Lian Wang, Hong Li, Hong Gong, Xiaotang Fan
Topics & Concepts
OrganoidNeurotoxicityMetaboliteEmbryonic stem cellEmbryoKetamineBiologyHuman brainCell biologyPharmacologyChemistryToxicologyInternal medicineMedicineNeuroscienceToxicityEndocrinologyBiochemistryGeneAnesthesia and Neurotoxicity Research3D Printing in Biomedical ResearchPluripotent Stem Cells Research