The Transcription Factor Roc1 Is a Key Regulator of Cellulose Degradation in the Wood-Decaying Mushroom <i>Schizophyllum commune</i>
Ioana M. Marian, Peter Jan Vonk, Iván Valdés, Kerrie Barry, Benedict Bostock, Akiko Carver, Chris Daum, Harry Lerner, Anna Lipzen, Hongjae Park, Margo B. P. Schuller, Martin Tegelaar, Andrew Tritt, Jeremy Schmutz, Jane Grimwood, Luis G. Lugones, In‐Geol Choi, Han A. B. Wösten, Igor V. Grigoriev, Robin A. Ohm
Abstract
. Roc1 is highly conserved in the phylum Basidiomycota. Using comparative genomics, transcriptomics, ChIP-Seq and promoter analysis we have identified direct targets of Roc1, as well as other aspects of the transcriptional response to cellulose.
Topics & Concepts
Schizophyllum communeBiologyAgaricomycetesCellobioseCellulaseBasidiomycotaFungal proteinMicrobiologyCelluloseBiochemistryGeneBotanyMutantFungal Biology and ApplicationsEnzyme-mediated dye degradationMycorrhizal Fungi and Plant Interactions