Green synthesis of cerium oxide nanoparticles using Citrus nobilis Lour. Peel extract and evaluation of their potential as antibacterial and antioxidant agents
Gusliani Eka Putri, Arniati Labanni, Syukri Arief, Putri Dafriani, Ika Yulia Darma, Sri Handayani, Widyastuti Widyastuti, Norzawani Jaffar, Marsal Mahmud, Ahmad Hafizullah Ritonga
Abstract
Cerium oxide nanoparticles (CeO 2 NPs) have been synthesized using Siam oranges ( Citrus nobilis Lour.) peel extract as a capping agent with varied concentration. X-ray diffraction (XRD) analysis confirmed the formation of cubic fluorite crystal structured CeO 2 NPs. Scanning electron microscope (SEM) and Transmission electron microscope (TEM) revealed that CeO 2 NPs were quasi-spherical with sizes ranging from 10 to 40 nm. The most optimum concentration of siam orange peel extract was 10%. IC50 value of 70.55 mg mL -1 indicates a strong antioxidant activity of sample. Additionally, the antibacterial activity showed that CeO 2 NPs were highly effective against S.aureus bacteria demonstrating their potential for biomedical applications.