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Electrochemical Oxidative Phosphorylation of Aldehyde Hydrazones

Zhongnan Xu, Yueheng Li, Guangquan Mo, Yucheng Zheng, Shaogao Zeng, Pinghua Sun, Zhixiong Ruan

2020Organic Letters55 citationsDOI

Abstract

The electrochemical phosphorylation of aldehyde hydrazones has been developed under exogenous oxidant-free conditions. The strategy provides expedient access to highly functionalized α-iminophosphine oxides with ample scope and broad functional group tolerance by means of mild, user-friendly electrolysis, in an undivided cell.

Topics & Concepts

ChemistryAldehydeOxidative phosphorylationElectrochemistryPhosphorylationElectrolysisScope (computer science)Combinatorial chemistryBulk electrolysisFunctional groupOrganic chemistryBiochemistryCatalysisComputer scienceCyclic voltammetryElectrodeElectrolytePhysical chemistryPolymerProgramming languageRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques
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