OXA-181-Producing Extraintestinal Pathogenic Escherichia coli Sequence Type 410 Isolated from a Dog in Portugal
Michael Brilhante, Juliana Menezes, Adriana Belas, Claudia Feudi, Štefan Schwarz, Constança Pomba, Vincent Perreten
Abstract
Two multidrug-resistant and carbapenemase-producing Escherichia coli clones of sequence type 410 were isolated from fecal samples of a dog with skin infection on admission to an animal hospital in Portugal and 1 month after discharge. Whole-genome sequencing revealed a 126,409-bp Col156/IncFIA/IncFII multidrug resistance plasmid and a 51,479-bp IncX3 bla OXA-181 -containing plasmid. The chromosome and plasmids carried virulence genes characteristic for uropathogenic E. coli , indicating that dogs may carry multidrug-resistant E. coli isolates related to those causing urinary tract infections in humans.
Topics & Concepts
PlasmidEscherichia coliBiologyMultiple drug resistanceVirulenceMicrobiologyFecesGeneWhole genome sequencingEnterobacteriaceaeGenomeGeneticsDrug resistanceEscherichia coli research studiesAntibiotic Resistance in BacteriaBacteriophages and microbial interactions