Biomimetic catalytic aerobic oxidation of C–sp(3)–H bonds under mild conditions using galactose oxidase model compound Cu<sup>II</sup>L
Xiaohui Liu, Haiyang Yu, Jiaying Huang, Ji‐Hu Su, Can Xue, Xiantai Zhou, Yaorong He, Qian He, Dejing Xu, Chao Xiong, Hongbing Ji
Abstract
A biomimetic catalytic approach for the aerobic oxidation of C–sp(3)–H bonds using galactose oxidase model compound was developed. EPR showed that the Cu I -radical intermediate species was critical for O 2 activation.
Topics & Concepts
Galactose oxidaseCatalysisChemistryIntramolecular forcePhthalimideRedoxPhotochemistrySubstrate (aquarium)Oxidase testRadicalStereochemistryGalactoseOrganic chemistryEnzymeGeologyOceanographyOxidative Organic Chemistry ReactionsMetal-Catalyzed Oxygenation MechanismsVanadium and Halogenation Chemistry