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What should be the entry pain intensity criteria for chronic pain clinical trials? An IMMPACT update

Dale J. Langford, Ralf Baron, Robert R. Edwards, Jennifer S. Gewandter, Ian Gilron, Robert Griffin, Peter Kamerman, Nathaniel P. Katz, Michael P. McDermott, Andrew S.C. Rice, Dennis C. Turk, Jan Vollert, Robert H. Dworkin

2023Pain16 citationsDOIOpen Access PDF

Abstract

In Brief Updated IMMPACT recommendations suggest minimum baseline pain intensity remain ≥4 of 10 for phase 2 and 3 clinical trials of chronic pain treatments.

Topics & Concepts

MedicineClinical trialChronic painIntensity (physics)Physical therapyInternal medicinePhysicsQuantum mechanicsPain Mechanisms and TreatmentsPain Management and Placebo EffectPain Management and Opioid Use
What should be the entry pain intensity criteria for chronic pain clinical trials? An IMMPACT update | Litcius