Quercetin attenuates diabetic neuropathic pain by inhibiting mTOR/p70S6K pathway-mediated changes of synaptic morphology and synaptic protein levels in spinal dorsal horn of db/db mice
Ruiyao Wang, Zhuang Qiu, Guizhi Wang, Qian Hu, Naihao Shi, Zongqin Zhang, Yuqing Wu, Chenghua Zhou
Topics & Concepts
Neuropathic painSynaptophysinSynaptic plasticityPostsynaptic potentialDendritic spineMedicinePostsynaptic densityPI3K/AKT/mTOR pathwayHyperalgesiaNeuroscienceChemistryPharmacologyEndocrinologyInternal medicineBiologyNociceptionSignal transductionHippocampal formationReceptorImmunohistochemistryBiochemistryPain Mechanisms and TreatmentsHealthcare and Venom ResearchHormonal and reproductive studies