<i>M. tuberculosis</i> PknG manipulates host autophagy flux to promote pathogen intracellular survival
Pupu Ge, Zehui Lei, Yang Yu, Zhe Lü, Lihua Qiang, Qiyao Chai, Yong Zhang, Dongdong Zhao, Bingxi Li, Yu Pang, Cui Hua Liu, Jing Wang
Abstract
: phosphatidylinositol(3,4,5)-trisphosphate; SQSTM1: sequestosome 1; STPK: serine-threonine protein kinase; TB: tuberculosis; TBC1D4: TBC1 domain family member 4; TPR: tetratricopeptide repeat; ULK1: unc-51 like autophagy activating kinase 1; WT: wild-type.
Topics & Concepts
AutophagyBiologyPleckstrin homology domainCell biologyProtein kinase BPI3K/AKT/mTOR pathwayKinaseBiochemistryATG5Protein kinase ASignal transductionApoptosisAutophagy in Disease and TherapyTuberculosis Research and EpidemiologyVibrio bacteria research studies