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Time dynamics of COVID-19

Cody Carroll, Satarupa Bhattacharjee, Yaqing Chen, Paromita Dubey, Jianing Fan, Álvaro Gajardo, Xiner Zhou, Hans-Georg Müller, Jane-Ling Wang

2020Scientific Reports47 citationsDOIOpen Access PDF

Abstract

We apply tools from functional data analysis to model cumulative trajectories of COVID-19 cases across countries, establishing a framework for quantifying and comparing cases and deaths across countries longitudinally. It emerges that a country's trajectory during an initial first month "priming period" largely determines how the situation unfolds subsequently. We also propose a method for forecasting case counts, which takes advantage of the common, latent information in the entire sample of curves, instead of just the history of a single country. Our framework facilitates to quantify the effects of demographic covariates and social mobility on doubling rates and case fatality rates through a time-varying regression model. Decreased workplace mobility is associated with lower doubling rates with a roughly 2 week delay, and case fatality rates exhibit a positive feedback pattern.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Case fatality rateEconometricsCovariateTrajectoryDemographySample (material)2019-20 coronavirus outbreakStatisticsRegressionComputer scienceMathematicsMedicineDiseasePathologyChemistrySociologyInfectious disease (medical specialty)ChromatographyOutbreakAstronomyPhysicsPopulationVirologyCOVID-19 epidemiological studiesCOVID-19 Pandemic ImpactsData-Driven Disease Surveillance
Time dynamics of COVID-19 | Litcius